Microparticle Assembly Pathways on Lipid Membranes

Lipid assembly into cell membranes

A fundamental problem of cell biology and biochemistry is the elucidation of the mechanisms by which the specific components of subcellular membranes are assembled into mature organelles. The major components of all cell membranes are lipids and proteins. The presence of discrete structural motifs contained in the primary sequence of proteins directs a large number of post-translational process...

The assembly and use of tethered bilayer lipid membranes (tBLMs).

Because they are firmly held in place, tethered bilayer lipid membranes (tBLMs) are considerably more robust than supported lipid bilayers such as black lipid membranes (BLMs) (Cornell et al. Nature 387(6633): 580-583, 1997). Here we describe the procedures required to assemble and test tethered lipid bilayers that can incorporate various lipid species, peptides, and ion channel proteins.

Variable tilt on lipid membranes.

A continuum theory for lipid membranes is developed that accounts for mechanical interactions between lipid tilt and membrane shape. For planar membranes, a linear version of the theory is used to predict tilt variations similar to those observed in experiments and molecular dynamics simulations.

Lipid peroxidation modifies the assembly of biological membranes “The Lipid Whisker Model”

The aim of this opinion article is to point out the basic principles that modify the assembly of biological membranes during lipid peroxidation. With this objective in mind, I describe: the structural and functional properties of membranes, the transport and diffusion of oxygen regulated by cholesterol and fatty acids; the “Lipid Whisker Model” and finally analyzed the changes induced by lipid ...

Lipid Membranes